Psoriasis is a condition that is not only found on the torso, arms and legs, but can also affect your hands and feet. When psoriasis affects your hands and a feet it can interfere with daily activities. There are several different treatments for hand and foot psoriasis. Most often topical steroids are the first line therapy. Alternative treatment options can be the use of laser, oral medications such as methotrexate or Soriatane, or "biologic" therapies such as Enbrel, Humira and Stelara which are injected under the skin.