What is Daxxify®?

Daxxify® is a revolutionary injectable medication used to relax frown lines. The neuromodulator is FDA-approved and works to help smooth moderate to severe lines between the brows by relaxing the underlying muscles that cause wrinkles.

The active ingredient in Daxxify® is a purified protein called botulinum toxin type A, the same found in BOTOX®, Dysport® and Xeomin®. The big difference is that Daxxify® has a peptide that helps keep the active ingredient stuck to the nerve terminal, giving a longer-lasting result. This means instead of the average 3-4 month duration with most neurotoxins like BOTOX®, Daxxify® can give you a 4-6 month duration of effect. Daxxify® also has a faster onset with effects showing as soon as 24 hours after treatment.

Daxxify® is also unique because it is the only FDA-approved neurotoxin that uses a peptide as a stabilizer and does not contain human or animal byproducts.

Advanced Dermatology is one of the first practices in Illinois to offer Daxxify®!skip to faq section below to learn more about Daxxify↓

What Does This Mean for You?

This means that you could have a treatment that lasts longer than your current neurotoxin. If your current treatment wears off after 3 months, for instance, Daxxify® might not wear off for 5 or 6 months. This is great news for people who have experienced a duration of less than 3-4 months, or for people who would prefer to come into the office only twice per. If you are happy with your current neuromodulators (i.e. BOTOX®, Dysport® or Xeomin®), there is no need to switch.


Advanced Dermatology was one of the clinical study sites for Daxxify®! It was the largest-ever group of clinical studies for a frown line treatment, including more than 2,800 people across different ages and skin types.

How Does Daxxify® Compare to BOTOX®?

Both Daxxify® and BOTOX® are injectable medications used to temporarily improve the appearance of facial wrinkles. However, there are some key differences.

One of the main differences is Daxxify® lasts longer than BOTOX® . Daxxify® can last for 4-6 months while BOTOX® typically lasts for 3-4 months. Additionally, Daxxify® generally acts faster with effects beginning to show just 24 hours after treatment®. Typically, it may be several days before BOTOX® takes effect.

Both treatments are made with botulinum toxin type A, but they differ in how they stabilize the toxin. BOTOX® uses proteins, while Daxxify® uses peptides.

How Long Does it Take for Daxxify® to Work?

You may see initial results with Daxxify® as early as 24 hours after treatment, and typically within two days. Most people will see noticeable results within two weeks. Initial results can include signs of reduced muscle activity and smoother appearance, while noticeable results are wrinkle reduction in the treated area.

Who makes Daxxify®?

Revance Therapeutics manufactures Daxxify® in California. Revance Therapeutics is a biotechnology company. Daxxify® states it is the only prescription frown line treatment made in the United States.

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