Dr. Taub quoted in Practical Dermatology
September Issue 2016, Vol 13, No 9
“DefenAge stands out in the saturated growth of the anti-aging industry due to its focus on molecular specificity as the science behind the skincare is to stimulate one locus of stem cells. These stem cell are found in the hair follicles. One particular stem cell locus called LGR6+, is responsible for renewal of skin cells lost to trauma and replacement of dead cells as well as being responsible for generating the entire epidermal cell line during embryonic life. Aging cells may have reduced function and contain mutations. Other growth factors stimulate these ‘tired cells’.
DefenAge products contain synthetic copies of the body’s natural defensins, which are secreted by neutrophils after trauma to turn on this stem cell locus to create new cells. These stem cells lay dormant until they are stimulated, thus are “new” and don’t carry mutations or other limitations of function that “tired cells” have. In other words, these defensis peptides trigger the skin’s own repair mechanism, ‘waking-up’ the skin and making appear as it did when we were younger. The products’ claim is that you will see a change in your skin’s dullness, wrinkling, and pigmentation. We have found this to be true in most of our patients, and are currently working on a placebo-controlled, double-blind study to prove this.” Read Full Article.