Regenerative Skin Solutions in Dermatology

One of the most common cosmetic concerns I see in practice is skin laxity, especially in the lower face and jawline. This is primarily due to the gradual breakdown of our skin’s structural proteins, collagen and elastin, which occurs naturally with aging. Collagen provides strength and support, while elastin allows the skin to stretch and return to its original position. With age, both fibers degrade and become disorganized, resulting in visible sagging and loss of skin resilience.

Regenerative treatments represent a major advancement in non-surgical skin tightening. Rather than simply masking the effects of aging, these therapies work by stimulating the body’s natural repair processes, prompting your own cells to rebuild lost structure. The foundation of this approach is understanding how the skin can still regenerate, even later in life, given the right biological signals.

Energy-based devices such as Sofwave™ (ultrasound) and radiofrequency technologies are at the forefront of this field. These devices deliver precise energy into the dermal layer, where fibroblasts, the cells responsible for producing collagen and elastin, reside. The controlled heat from these treatments creates a mild, targeted injury that triggers a wound healing response. This response prompts fibroblasts to increase the production of new, well-organized collagen and to repair or replace dysfunctional elastin fibers. Importantly, these treatments are non-invasive and require minimal downtime.

Our clinical research, published in Dermatologic Surgery, demonstrated that Sofwave™ led to significant and measurable improvements in skin firmness and a reduction in laxity, both in the jawline and upper arms. The study’s methodology relied on blinded assessment of standardized before-and-after photographs, providing objective validation of results. This data was integral in obtaining FDA approval for Sofwave™ in treating upper arm laxity.

In addition to device-based therapy, I also use biostimulatory injectables such as Sculptra®. Sculptra® is made of poly-L-lactic acid and is classified as a biostimulator rather than a traditional filler. Instead of providing immediate volume, Sculptra® acts over several weeks to months by stimulating fibroblasts to synthesize new collagen. The end result is a gradual but meaningful improvement in skin thickness, firmness, and elasticity.

Often, combining regenerative approaches yields optimal outcomes. For example, pairing Sofwave™ with Sculptra® can address both immediate and long-term structural concerns by activating multiple pathways in skin repair and rejuvenation.

In addition to in-office regenerative procedures, we can now leverage regenerative medicine directly in your daily skincare routine with products that use exosome technology. Exosomes are microscopic messengers that deliver growth factors, proteins, and genetic material between skin cells, instructing them to repair, regenerate, and optimize function. In dermatology, exosome technology represents a cutting-edge advance because it helps to restore and maintain the skin’s own youthful biology.

Now available at skinfo®, the plated™ skincare line including plated™ Intense and plated™ Daily, uses exosomes derived from human platelets, which are naturally rich in growth factors crucial for tissue repair and regeneration. By delivering these bioactive signals directly to your skin, plated™ products help support collagen synthesis, improve firmness, enhance radiance, and accelerate the skin’s healing response.

We recommend plated™ Intense and plated™ Daily to patients looking to boost their skin’s regenerative capacity at home—either as a complement to in-office treatments or as a standalone approach for daily maintenance. Patients often report smoother, firmer, and more resilient skin after consistent use.

Regenerative treatments fundamentally differ from older approaches by harnessing and enhancing the body’s own ability to restore youthful structure. This shift means patients can expect natural results that improve progressively over time, rather than temporary masking of symptoms.

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